Can a person experience alcohol withdrawal symptoms after only their first drink?

Experiencing alcohol withdrawal symptoms after only the first drink is indeed possible, although it is quite rare. This phenomenon can occur in certain individuals who may have a predisposition to alcohol use disorder or who may have an underlying medical condition. For instance, individuals with a history of alcohol dependency or those who have engaged in heavy drinking in the past may experience withdrawal symptoms even after consuming alcohol only once again.

Moreover, some people may be particularly sensitive to changes in their body's chemistry and may develop a physical dependence more swiftly than others. Withdrawal symptoms are generally associated with prolonged and heavy alcohol consumption, but they can occur in any case where the body is not able to adjust rapidly to the presence of alcohol.

The other options suggest that multiple exposures are necessary or that certain populations are exempt from this possibility, which does not account for the individual variations in physiology and personal history regarding alcohol use.